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L-Alanine
CAS No.:56-41-7
Molecular Formula: C3H7NO2 Molecular Weight: 89.09
Molecular Structure:
Property:
Alanine is white powder. The melting point of Alanine is 314-316 ℃ and the alpha is 14.5 º (c=10,6N HCl, dry sub.), The water solubility of Alanine is166.5g/l (25℃). The deamination of an Alanine molecule produces a stable alkyl free radical, CH3C•HCOO–. Deamination can be induced in solid or aqueous alanine by radiation.
This property of Alanine is used in dosimetric measurements in radiotherapy. When normal Alanine is irradiated. The radiation causes certain Alanine molecules to become free radicals, and, as these radicals are stable, the free radical content can later be measured in order to find out how much radiation the Alanine was exposed to. In this way, one can be assured that complex radiotherapy treatment plans will deliver the intended pattern of radiation dose.
Specifications：
| Item | Index |
| Content(%) | 98.5～101.0 |
| D20Specific Rotation | ＋14.3°～＋15.2° |
| Transmittance % | ≥98.0 |
| Loss on Drying% | ≤0.20 |
| Residue on Ignition% | ≤0.1 |
| Other Amino Acids | None |
| Chloride[CIˉ] % | ≤0.02 |
| Sulfate[SO42-]% | ≤0.02 |
| Ammonium Salt [NH4+]% | ≤0.02 |
| Iron[Fe] ppm | ≤10 |
| Heavy Metals (Pb) ppm | ≤10 |
| Arsenic (As) ppm | ≤1 |
| PH | 5.7～6.7 |
Usage:
Alanine plays a key role in Glucose–Alanine cycle between tissues and liver. In muscle and other tissues that degrade amino acids for fuel, amino groups are collected in the form of glutamate by transamination. Glutamate can then transfer its amino group through the action of Alanine aminotransferase to Pyruvate, a product of muscle glycolysis, forming Alanine and α-Ketoglutarate. The Alanine formed is passed into the blood and transported to the liver. A reverse of the Alanine aminotransferase reaction takes place in liver. Pyruvate regenerated forms Glucose through Gluconeogenesis, which returns to muscle through the circulation system. Glutamate in the liver enters mitochondria and degrades into Ammonium ion through the action of glutamate dehydrogenase, which in turn participate in the urea cycle to form urea.
The Glucose–Alanine cycle enables Pyruvate and Glutamate to be removed from the muscle and find their way to the liver. Glucose is regenerated from Pyruvate and then returned to muscle: the energetic burden of Gluconeogenesis is thus imposed on the liver instead of the muscle. All available ATP in muscle is devoted to muscle contraction.
Package and Storage:
Alanine is packed in 25kg fiber drum and stored in cool and air place.
Keyword:
Alanine, 2-Aminopropanoic Acid