USP27

CAS No.: 79-81-2

Molecular Formula: C₃₆H₆₀O₂ Molecular Weight: 524.87

Structural Formula:

Property:

Vitamin A Palmitate is a free flowing, fine, spraydired, granular powder. The particle of Vitamin A Palmitate has a spherical-shaped coating and contains Vitamin A Palmitate, modified starch and vegetable oil etc. Therefore, the particular coating process and presence of high-purity of Vitamin A Palmitate could completely ensure the stability.

Specification:

Identification	Positive
Assay	1.70 M.I.U./G Min
Absorbance ratio (325nm)	0.85Min
Peroxides	1.0 mL of 0.01mol/L Na2S2O3 Max
Acid Value	2.0 Max

Usage:

Dietary supplements:

Vitamin A Palmitate is used for preparations with a lipophilic base, e.g. soft gelatin capsules.

Pharmaceutical products:

Both EU Drug Master File and US Drug Master.File are available. Vitamin A Palmitate is particularly suitable for manufacturing aqueous solutions using solubilizing agents such as Cremophor EL or Cremophor RH 40 for oral administration and Solutol. HS 15 for parenteral use. The chart shows the required quantity of Cremophor RH 40 for the solubilization of proportional quantities of Vitamin A Palmitate. Sterilization of the final product is required for parenteral use.

Food products:

Vitamin A Palmitate is used for the fortification of fatty foods such asmargarine, spreads, oils, milk and dairy products. Quantities of 3-9 mg (10,000-30,000 IU) of Vitamin A Palmitate, calculated as retinol, are usually added per kg of margarine. The regulations are governing the use of BHT must be observed.

Cosmetics:

Vitamin A Palmitate is for use in cosmetic oils, emulsions (creams, lotions, body milk, gels etc.) and other preparations, e.g. lipstick, masks. A solubilizing agent is required if the product is to be used in an aqueous/alcoholic preparation. The maximum quantities are legally permitted for use in cosmetics must be observed.

Packing:

Vitamin A Palmitate is packed in iron barrel or aluminium container, with N2 in it. Vitamin A Palmitate should be stored in cool and air place.

Shelf life:

1 year in original packages under the described conditions.

Keyword:

Vitamin A Palmitate