CAS NO.: 24390-14-5
EINECS: N
Molecular Formula: C22H24N2O8.HCl
Molecular
Weight:
480.90
Molecular Structure:

Property:
The physical state of doxycycline hyclate is
yellowish crystalline powder. Doxycycline hyclate is soluble
in water.
Specifications:
|
Item |
Index |
| Appearance |
Yellow crystalline
powder |
| Identification |
A) HPLC test
B) Sulphuric acid yellow color reaction
C) Chloride’s reaction |
|
Specific Optical Rotation |
-105 to
-120,calculated on the anhydrous,ethanol-free
substance |
| Specific
Absorbance |
300-335 at
349nm,calculated on the anhydrous,ethanol-free
substance |
| Light-absorbing
Impurities |
Not more than 0.07 at
490nm,calculated on the anhydrous,ethanol-free
substance |
| Related
Substances |
|
|
Metacycline |
Not more than 2.0% |
|
6-epidoxycycline |
Not more than 2.0% |
| Any Individual
Impurities |
Not more than 0.5% |
| Disregard Limit |
Not more than 0.1% |
| Ethanol |
4.3 to 6.0% |
| Heavy Metals |
Less than 50ppm |
| Water |
1.4% to 2.8% |
| Sulphated Ash |
Not more than 0.4% |
| Assay |
95.0-102.0 % of C22H24N2O8.HCl calculated on the anhydrous,ethanol-free substance |
Usage:
Treating certain bacterial infections.
Doxycycline Hyclate may be used in combination with
other medicines to treat acne or certain amoeba
infections. Doxycycline Hyclate may be used to prevent
certain types of malaria in travelers who will be
visiting malaria-infected areas for less than 4 months.
Doxycycline Hyclate may also be used to prevent or slow
the progression of anthrax after exposure.
Doxycycline Hyclate is a tetracycline
antibiotic. Doxycycline Hyclate works by slowing the growth
of bacteria. Slowing the bacteria's growth allows the body's
immune system to destroy the bacteria.
Package and Storage:
Doxycycline Hyclate is kept in shaded,
cool 25kg fiber drum and air places. The shelf time is 4
years.
Keyword:
Doxycycline hyclate ,Doxycycline hydrochloride
hemiethanolate; 2-(Amino-hydroxy-methylidene)-4-dimethylamino-5,10,11,12a-tetrahydroxy-6-methyl-4a,5,5a,6-tetrahydro-4H-tetracene-1,3,12-trione
hydrochloride hemiethanolate