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Doxycycline Hyclate

CAS NO.: 24390-14-5                                   EINECS: N

Molecular Formula: C22H24N2O8.HCl       Molecular Weight: 480.90

Molecular Structure:

Property:

The physical state of doxycycline hyclate is yellowish crystalline powder. Doxycycline hyclate is soluble in water.

Specifications:

Item Index
Appearance Yellow crystalline powder
Identification A) HPLC test
B) Sulphuric acid yellow color reaction
C) Chloride’s reaction
Specific Optical Rotation -105 to -120,calculated on the anhydrous,ethanol-free substance
Specific Absorbance 300-335 at 349nm,calculated on the anhydrous,ethanol-free substance
Light-absorbing Impurities Not more than 0.07 at 490nm,calculated on the anhydrous,ethanol-free substance
Related Substances  
Metacycline Not more than 2.0%
6-epidoxycycline Not more than 2.0%
Any Individual Impurities Not more than 0.5%
Disregard Limit Not more than 0.1%
Ethanol 4.3 to 6.0%
Heavy Metals Less than 50ppm
Water 1.4% to 2.8%
Sulphated Ash Not more than 0.4%
Assay 95.0-102.0 % of C22H24N2O8.HCl calculated on the anhydrous,ethanol-free substance

Usage:

Treating certain bacterial infections. Doxycycline Hyclate may be used in combination with other medicines to treat acne or certain amoeba infections. Doxycycline Hyclate may be used to prevent certain types of malaria in travelers who will be visiting malaria-infected areas for less than 4 months. Doxycycline Hyclate may also be used to prevent or slow the progression of anthrax after exposure.

Doxycycline Hyclate is a tetracycline antibiotic. Doxycycline Hyclate works by slowing the growth of bacteria. Slowing the bacteria's growth allows the body's immune system to destroy the bacteria.

Package and Storage:

Doxycycline Hyclate is kept in shaded, cool 25kg fiber drum and air places. The shelf time is 4 years.

Keyword:

Doxycycline hyclate ,Doxycycline hydrochloride hemiethanolate; 2-(Amino-hydroxy-methylidene)-4-dimethylamino-5,10,11,12a-tetrahydroxy-6-methyl-4a,5,5a,6-tetrahydro-4H-tetracene-1,3,12-trione hydrochloride hemiethanolate

 

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