IvermectinCAS NO.: 70288-86-7 EINECS: 274-536-0 Molecular Formula: C48H74O14 Molecular Weight: 875.11 Molecular Structure:
Property:Ivermectin is a broad-spectrum antiparasitic avermectin medicine. Ivermectin is sold under brand names Stromectol in the United States, Mectizan in Canada by Merck and Ivexterm in Mexico by Valeant Pharmaceuticals International Specifications：
Usage:Ivermectin is a broad-spectrum antiparasitic agent. Helminth Ivermectin is traditionally used against worms. Ivermectin is mainly used in humans in the treatment of onchocerciasis, but is also effective against other worm infestations (such as strongyloidiasis, ascariasis, trichuriasis, filariasis and enterobiasis). Ivermectin, under the brand name Mectizan, is currently being used to help eliminate river blindness (onchocerciasis) in the Americas and stop transmission of lymphatic filariasis and onchocerciasis around the world. Currently, large amounts of ivermectin are donated by Merck to fight river blindness in countries that are unable to afford the drug. The disease is endemic in 30 African countries, 6 Latin American countries and Yemen, according to studies conducted by the World Health Organization. The drug rapidly kills microfilariae, but not the adult worms. A single oral dose of ivermectin, taken annually for the 10-15 year life span of the adult worms, is all that is needed to protect the individual from onchocerciasis. Arthropod More recent evidence supports its off-label use against arthropods: Mites such as Scabies. Ivermectin is usually limited to cases that prove resistant to topical treatments and/or who present in advanced state (such as Norwegian scabies). Lice Veterinary use Ivermectin is also used in veterinary medicine. Ivermectin is sometimes administered in combination with other medications to treat a broad spectrum of animal parasites. Some dog breeds (especially the Rough Collie, the Smooth Collie and the Australian Shepherd) have a high incidence of a certain mutation within the MDR1 gene; affected animals are particularly sensitive to the toxic effects of ivermectin. Kittens are also very sensitive. Ivermectin is sometimes used as an acaricide in reptiles, both by injection and as a diluted spray. While this works really well in some cases, care must be taken as several species of reptile are very sensitive to ivermectin. Use in turtles is particularly contraindicated. Package and Storage:Keep in shaded, cool 25kg fiber drum and air places. The shelf time is 2 years. Key Words:Ivermectin ,Ivomec; Heartgard-30 |
