Oxibendazole

CAS NO.: 20559-55-1 EINECS: 243-877-7

Molecular Formula: C₁₂H₁₅N₃O₃ Molecular Weight: 249.27

Molecular Structure:

Property:

Oxibendazole acts by disrupting the generation of ATP and irreversibly inhibiting glucose uptake in the gastro-intestinal worms resulting in a depletion of the worm’s energy sources and their slow death.Oxibendazole is a benzimidazole anthelmintic used in the treatment of roundworms, strongyles, threadworms, pinworms and lungworm infestations in horses and other ruminants. Oxibendazole was highly effective against adult large strongylids (Strongylus vulgaris, S edentatus, S equins), adult small strongylids (especially species of the genera Cylicostephanus, Cylicocyclus, Cyaathostomum, and Triodontophorus), and adult and larval stages of the large pinworm, Oxyuris equi.

Specifications：

Item	Index
Description	White to off white powder.
Solubility	Soluble in Acetic & Formic Acid
Identification A) Infra-red	Complies
Related Substances (TLC)	Single spot
Melting Range	About 233°C
Loss on Drying	NMT 1.0% w/w
Sulphated Ash	NMT 0.5% w/w
Assay (On Dried Basis)	98% to 102% w/w
(Non Aqeous)
Pharmacopoeial Standards	As per B.P.Vet

Usage:

Oxibendazole is a benzimidazole drug that is used to protect against roundworms, strongyles, threadworms, pinworms and lungworm infestations in horses and some domestic pets. Oxibendazole is usually white to yellowish in appearance, and may take the form of a powder or a tablet.Oxibendazole can be synthesized from acetominophen by the following route.

Package and Storage:

25kg fiber drum in cool and air place.

Key Words:

Oxibendazole ,Methyl (5-propoxy-1H-benzimidazol-2-yl)carbamate