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Oxytetracycline Base

CAS NO.: 6153-64-6                                                        EINECS: N

Molecular Formula: C22H24N2O9.2H2O                       Molecular Weight: 496.90

Molecular Structure:

 

Property:

The melting point of Oxytetracycline Base is 181-182 ºC.The alpha of Oxytetracycline Base is -216 º (c=1,0.1 M HCl) .The water solubility of Oxytetracycline Base is slightly soluble.

Specifications:

Item Index
Characters Yellow powder (Ph. Eur.)
Identification Ph. Eur. , USP
Absorbance 353 nm, E (1%) – 290 – 310 (Ph. Eur.) 353 nm, 96% –104% (USP)
Specific optical rotation -203° – -216°(Ph. Eur.)
Light absorbing impurities 430nm≤0.25(Ph. Eur.) 490nm≤0.20
Related substances 4-Epioxytetracycline≤0.5% Tetracycline hydrochloride≤2.0% Peak on the tail of the mail peak≤2.0%
Heavy metals ≤50ppm (Ph. Eur.)
Sulphated ash ≤0.5% (Ph. Eur.)
Water 6.0-9.0 (USP, Ph. Eur.)
Assay (HPLC) 95.0% - 102.0% (Ph. Eur.) (Based on anhydrous substance) ≥832μg/mg (Original) (USP)

Usage:

Oxytetracycline is an antibiotic with broad antibacterial spectrum.Oxytetracycline is mainly used in the treatment of rickettsiosis, brucellosis, mycoplasma,pneumonia and chlamydia infections. Oxytetracycline can also be used to treat slight infections that caused by sensitive gram-positive coccus and gram-negative bacillus.

Package and Storage:

25kg/bag or as per customers' requests.Sealed and kept in dry place, protected from light

Key Words:

Oxytetracycline ,Hydroxytetracycline,3,5,6,10,12,12a-hexahydroxy-6-methyl-1,11-dioxo-2-naphthacenecarboxamide dihydrate

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