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Toltrazuril

CAS NO.: 108050-54-0                                                 EINECS: N             

Molecular Formula: C46H80N2O13                           Molecular Weight: 869.15

Molecular Structure:

 

Property:

Tilmicosin is a macrolide antibiotic developed for veterinary use. Tilmicosin is recommended for treatment and prevention of pneumonia in cattle, sheep and pigs, associated with Pasteurella haemolytica, P. Multocida, Actinobacillus pleuropneumoniae, mycoplasma species and other microorganisms found sensitive to this compound.

Tilmicosin is freely soluble (1500 mg/L or greater) in organic solvents (hexane, acetone, acetonitrile, chloroform, dichloromethane, ethyl acetate, methanol, tetrahydrofuran); water solubility is temperature and pH dependent, but is 566 mg/mL at pH 7 and 25°C.

Specifications:

Item Index
Appearance White to off-white powder
Water Less than 5.0%
Assay More than 85.0% ( Tilmicosin on dry basis)
Cis-isomer 82.0% - 88.0%
Trans-isomer 12.0% - 18.0

Usage:

Tilmicosin is a macrolide antibiotic developed for veterinary use. Tilmicosin is recommended for treatment and prevention of pneumonia in cattle, sheep and pigs, associated with Pasteurella haemolytica, P. multocida, Actinobacillus pleuropneumoniae, mycoplasma species and other microorganisms found sensitive to this compound. Tilmicosin has not been previously reviewed by the Committee.

Package and Storage:

25kg fiber drum and kept in air condition place for 2 years.

Key Words:

Tilmicosin ,20-Deoxo-20-(3,5-dimethyl-1-piperidinyl)desmycosin

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